Is it Time to Reassess the SITS-MOST Criteria for Thrombolysis?

Is it time to reassess the SITS-MOST criteria for thrombolysis?: A comparison of patients with and without SITS-MOST exclusion criteria.

BACKGROUND AND PURPOSE The Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST) established guidelines to increase safety in acute stroke thrombolysis, but precluding treatment in an important proportion of patients. We aimed to assess safety/efficacy of thrombolysis in patients with SITS-MOST exclusion criteria. METHODS 369 nonlacunar tPA-treated patients were studied. ...

Coronary angiography: is it time to reassess?

Communication of scientific information: is it time to reassess?

The format of communicating scientific, technical, and medical (STM) information through professional journals has changed relatively little since the publication in 1665 of the Philosophical Transactions of the Royal Society, the world’s first journal devoted exclusively to science. Although advances in information technology have dramatically altered the search and discovery of scientific inf...

Statins: is it really time to reassess benefits and risks?

search need. Evaluating the HBV viral load in HIV-infected pregnant women should be an essential step of prenatal evaluation, so that the mother’s health can be managed appropriately. Continued improvements in the coverage and timeliness of HBV vaccination and the education of clinicians about its importance should be priorities everywhere. Making such improvements will require substantial advo...

Is It Time to Say Farewell to the ISDS System?; Comment on “The Trans-Pacific Partnership: Is It Everything We Feared for Health?”

Investor-state dispute settlement (ISDS) continues to plague health-oriented government regulation. This is particularly reflected in recent challenges to tobacco control measures through bilateral investment agreements. There are numerous reform proposals circulating within the public health community. However, I suggest that perhaps it is time for the community to explore a stronger position ...